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About CF

Cystic fibrosis is a progressive, genetic disease that causes persistent lung infections and limits the ability to breathe over time. In people with cystic fibrosis, a defective gene causes a thick buildup of mucus in the lungs, pancreas and other organs. In the lungs, mucus clogs the airways and traps bacteria, leading to infections, extensive lung damage and respiratory failure.

The mission of the Cystic Fibrosis Foundation is to cure cystic fibrosis and to provide all people with CF the opportunity to lead long, fulfilling lives by funding research and drug development, partnering with the CF community, and advancing high-quality, specialized care.

Since 2020, the CF Foundation has funded more than $1 billion in research and care awards, with highlights of approximately:

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Genetic therapies are our best chance for helping people with CF. These therapies are more complex than anything we have ever pursued and require substantial investment. Progressing a genetic therapy could cost the Foundation 10 times more than the development of a life-changing modulator treatments just a decade ago.

Let's End CF

With your support, we can reach the finish line. Together we can help end cystic fibrosis.​ 

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To learn more about CF or the Cystic Fibrosis Foundation, please visit cff.org.

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